Opportunity Information: Apply for CDC RFA GH16 17200101SUPP19

The "Strengthening Public Health Laboratories Internationally" grant opportunity is a CDC cooperative agreement designed to help countries build and sustain strong national public health laboratory (NPHL) systems as part of the U.S. Government's Global Health Security Agenda (GHSA). GHSA is positioned as a practical framework for helping nations meet the International Health Regulations (2005) requirements, with this funding focused specifically on IHR Core Capacity 8 (laboratory). In plain terms, the opportunity is meant to improve how countries organize, run, and connect their laboratory services so they can detect, confirm, and characterize high-impact pathogens quickly and safely, and then translate lab results into timely public health action.

The program centers on developing "tiered" laboratory services that follow international best practices and standards. A tiered model generally means laboratories at different levels of the health system (for example, national reference labs, regional labs, and local or peripheral labs) each perform roles that match their capability, with clear referral pathways for more specialized testing. The CDC emphasizes that a resilient national system is not only a single central lab, but a coordinated network that includes public and private laboratories and spans multiple sectors: clinical laboratories, public health laboratories, veterinary labs, food safety labs, and environmental labs. The intent is to integrate these labs into the country's broader healthcare and surveillance systems so that information flows efficiently, specimens can be referred correctly, and results can support surveillance and outbreak response across the whole country.

The main technical areas highlighted map closely to the components of IHR laboratory capacity. This includes strengthening national policy and coordination for laboratory services, improving diagnostic and confirmatory testing capacity, and enhancing laboratory biosafety and biosecurity so work is conducted in a safety-minded and secure environment. Another major emphasis is laboratory-based surveillance: ensuring that laboratories are not just doing tests in isolation, but are producing quality-controlled data that feeds into disease monitoring systems, helps differentiate and characterize new or emerging threats, and supports evidence-based decisions by public health authorities. The overall aim is faster, more reliable detection and reporting of epidemic-prone diseases and other serious health threats, enabling authorities to respond rapidly and effectively.

CDC also frames the need for this investment around persistent global vulnerabilities that continue to put countries at risk despite progress in recent decades. These gaps include weak or uneven disease surveillance in certain geographic areas, institutional and logistical barriers that slow service delivery, challenges and hesitancy around sharing outbreak information or biological samples, the ongoing emergence of new pathogens, increasing antimicrobial and drug resistance, limited public health protections at borders, and the possibility of intentional or accidental release of biological agents. The funding opportunity argues that strengthening laboratory systems is a practical way to reduce these vulnerabilities by improving prevention, detection, and response capacity for outbreaks, potential Public Health Emergencies of International Concern (PHEICs), and other major public health events.

From an administrative standpoint, this is a discretionary funding opportunity from the Department of Health and Human Services, Centers for Disease Control and Prevention (CDC), under CFDA 93.318, using a cooperative agreement mechanism. A cooperative agreement typically means the CDC expects to have substantial involvement in the work, such as providing technical guidance, collaboration, and oversight rather than simply issuing a grant with minimal federal interaction. The opportunity was posted under Funding Opportunity Number CDC RFA GH16-17200101SUPP19, with an anticipated single award (Expected Awards: 1) and an award ceiling of $10,000,000. The original application closing date listed was August 19, 2019, with electronic submissions due by 11:59 p.m. Eastern Time. Eligibility is noted broadly as "Others" with additional clarification referenced in the full announcement, suggesting that applicants needed to consult the eligibility section for specific details on which organizations could apply.

Taken together, the opportunity is essentially about building a connected, quality-driven national laboratory ecosystem that can safely and accurately detect priority health threats, support surveillance with actionable data, and strengthen a country's ability to meet international health security expectations under IHR and GHSA.

  • The Department of Health and Human Services, Centers for Disease Control - CGH in the health sector is offering a public funding opportunity titled "Strengthening Public Health Laboratories Internationally" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.318.
  • This funding opportunity was created on Jul 18, 2019.
  • Applicants must submit their applications by Aug 19, 2019 Electronically submitted applications must be submitted no later than 1159 p.m., ET, on the listed application due date.. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Each selected applicant is eligible to receive up to $10,000,000.00 in funding.
  • The number of recipients for this funding is limited to 1 candidate(s).
  • Eligible applicants include: Others (see text field entitled Additional Information on Eligibility for clarification).
Apply for CDC RFA GH16 17200101SUPP19

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Frequently Asked Questions (FAQs)

What is the "Strengthening Public Health Laboratories Internationally" grant opportunity?

It is a CDC cooperative agreement intended to help countries build and sustain strong national public health laboratory (NPHL) systems. The focus is on improving how laboratory services are organized, operated, and connected so countries can detect, confirm, and characterize high-impact pathogens quickly and safely, and then turn laboratory findings into timely public health action.

Who is the funder and what type of award is this?

The funder is the U.S. Department of Health and Human Services (HHS), Centers for Disease Control and Prevention (CDC). The mechanism is a cooperative agreement, meaning CDC expects to have substantial involvement (for example, technical guidance, collaboration, and oversight) rather than providing a grant with minimal federal interaction.

How does this opportunity relate to the Global Health Security Agenda (GHSA)?

This funding is positioned as part of the U.S. Government's Global Health Security Agenda (GHSA). GHSA is described as a practical framework that helps nations meet the International Health Regulations (2005) requirements, and this particular opportunity targets laboratory system strengthening as a key part of that agenda.

Which International Health Regulations (2005) capacity does the funding emphasize?

The opportunity focuses specifically on IHR Core Capacity 8 (laboratory). In practical terms, that means strengthening the national laboratory system so it can support surveillance and outbreak response with reliable, timely, and safe testing and reporting.

What is the main purpose of the funding in plain terms?

The purpose is to improve national laboratory ecosystems so that specimens can be tested and referred appropriately, results can be produced quickly and safely, and laboratory data can be used to guide surveillance and rapid public health response to serious health threats.

What does CDC mean by a "tiered" laboratory system?

A tiered model generally means laboratories at different levels of the health system (for example, national reference labs, regional labs, and local/peripheral labs) each perform roles aligned with their capabilities. The system includes clear referral pathways so more specialized testing can be performed at higher-tier laboratories when needed.

Is the goal to strengthen one central national laboratory or a wider network?

The intent is to strengthen a coordinated national network, not just a single central laboratory. CDC emphasizes a resilient national system as a connected laboratory network that can function across the country and support public health decision-making.

Do public and private laboratories both matter under this opportunity?

Yes. The opportunity emphasizes a coordinated network that includes both public and private laboratories, integrated into the broader healthcare and surveillance systems to support efficient information flow, specimen referral, and use of results for public health action.

Which sectors are expected to be included in the national laboratory network?

The opportunity describes a multi-sector approach that can span clinical laboratories, public health laboratories, veterinary laboratories, food safety laboratories, and environmental laboratories.

What kinds of improvements are targeted in national laboratory services?

The technical areas highlighted include strengthening national policy and coordination for laboratory services, improving diagnostic and confirmatory testing capacity, enhancing laboratory biosafety and biosecurity, and ensuring laboratory data supports surveillance and outbreak response.

What is meant by "diagnostic and confirmatory testing capacity" in this program?

It refers to improving the ability of the laboratory system to detect, confirm, and characterize high-impact pathogens. The aim is faster and more reliable testing and reporting to enable timely public health action.

How important are biosafety and biosecurity in this opportunity?

They are a major emphasis. The opportunity highlights enhancing laboratory biosafety and biosecurity so that laboratory work is conducted in a safety-minded and secure environment.

What is "laboratory-based surveillance" and why is it emphasized?

Laboratory-based surveillance means laboratories are not just running tests in isolation. Instead, they produce quality-controlled data that feeds into disease monitoring systems, supports differentiation and characterization of emerging threats, and helps public health authorities make evidence-based decisions.

What public health outcomes is CDC trying to improve through this funding?

The overall aim is faster, more reliable detection and reporting of epidemic-prone diseases and other serious health threats, enabling authorities to respond rapidly and effectively, including for potential Public Health Emergencies of International Concern (PHEICs).

What kinds of vulnerabilities does CDC cite as reasons for investing in laboratory systems?

The opportunity cites persistent global vulnerabilities such as weak or uneven surveillance in some geographic areas, institutional and logistical barriers that slow service delivery, challenges and hesitancy around sharing outbreak information or biological samples, emergence of new pathogens, increasing antimicrobial and drug resistance, limited protections at borders, and the possibility of intentional or accidental release of biological agents.

How does strengthening laboratories help address these vulnerabilities?

The opportunity frames laboratory system strengthening as a practical way to reduce vulnerabilities by improving prevention, detection, and response capacity for outbreaks and other major public health events, including potential PHEICs.

What is the Funding Opportunity Number (FON) for this announcement?

The Funding Opportunity Number listed is CDC RFA GH16-17200101SUPP19.

What is the CFDA number associated with this opportunity?

The opportunity is listed under CFDA 93.318.

How many awards were expected?

The announcement indicated an anticipated single award (Expected Awards: 1).

What was the maximum (ceiling) award amount?

The award ceiling listed was $10,000,000.

When was the application due date for the opportunity as posted?

The original application closing date listed was August 19, 2019, with electronic submissions due by 11:59 p.m. Eastern Time.

What does the eligibility category "Others" mean here?

The eligibility field is described broadly as "Others" with a note that additional clarification is referenced in the full announcement. Based on the information provided, applicants would have needed to consult the eligibility section in the full funding announcement for the specific eligible organization types.

What does "cooperative agreement" imply for how CDC works with the recipient?

It implies CDC expects substantial involvement in the work. Rather than only providing funds, CDC may provide technical guidance, collaborate on implementation, and have an oversight role during the project.

What does it mean to "integrate" laboratories into broader healthcare and surveillance systems?

It means establishing efficient pathways so specimens can be referred correctly, information can flow between laboratories and public health authorities, and laboratory results can be used to support surveillance and outbreak response across the country.

Is the opportunity focused only on testing, or also on how laboratories are coordinated and managed?

It covers more than testing. The opportunity highlights strengthening national policy and coordination for laboratory services, building a connected tiered network, improving biosafety and biosecurity, and ensuring results translate into timely public health action through surveillance and response systems.

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