Opportunity Information: Apply for PAR 21 273
The Maximizing Opportunities for Scientific and Academic Independent Careers (MOSAIC) Postdoctoral Career Transition Award to Promote Diversity is an NIH K99/R00 career transition grant (Funding Opportunity Number PAR-21-273) meant to help outstanding postdoctoral researchers from diverse backgrounds move more quickly and successfully from mentored postdoctoral training into independent, tenure-track (or equivalent) faculty positions at research-intensive institutions. Its core purpose is workforce-focused: building a stronger, more diverse pool of independent investigators in NIH mission areas, with an emphasis on strengthening diversity within the basic biomedical sciences. This particular announcement is the version that requires Independent Basic Experimental Studies with Humans (often abbreviated BESH), meaning the proposed research is expected to involve basic experimental work with human participants in ways that fit NIH definitions for that category.
The structure is the classic two-phase K99/R00 model. The K99 phase supports the final stage of mentored postdoctoral development, where the applicant builds additional skills, publications, preliminary data, and a clear plan for independence under the guidance of mentors. The R00 phase provides support after the awardee secures an independent faculty position, helping them establish their own lab or research program and compete effectively for future independent NIH research funding. In plain terms, the program is designed to reduce the gap between being a postdoc and being a fully independent principal investigator by providing a bridge of support across the career transition, rather than ending support right when the researcher takes on a new faculty role.
A defining feature of MOSAIC, beyond the financial support, is the cohort and community component. Awardees do not just receive a grant; they become MOSAIC scholars who are expected to participate in organized mentoring, networking, and professional development activities. These activities are coordinated by separate NIH-funded organizations supported through the MOSAIC Institutionally-Focused Research Education Award to Promote Diversity (UE5) mechanism. The idea is to combine research funding with structured career development, peer networking, and mentoring infrastructure, so participants get both resources and a professional community designed to increase retention and success in academic biomedical research careers.
Eligibility in the source information is broad in terms of organizational applicants and includes many types of domestic entities, such as public and private institutions of higher education, nonprofits (including 501(c)(3) and non-501(c)(3)), for-profit organizations (other than small businesses), small businesses, and multiple levels of government (state, county, city/township, special districts), as well as Native American tribal governments (federally recognized) and tribal organizations (other than federally recognized governments). The opportunity also explicitly notes additional eligible applicant categories that align with institutions serving historically underrepresented groups and communities, including Historically Black Colleges and Universities (HBCUs), Hispanic-serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, and Asian American Native American Pacific Islander Serving Institutions (AANAPISIs), along with faith-based or community-based organizations, eligible federal agencies, regional organizations, and U.S. territories or possessions. At the same time, the announcement draws clear boundaries around foreign involvement: non-domestic (non-U.S.) entities and non-domestic components of U.S. organizations are not eligible to apply, although foreign components may be allowed as defined under the NIH Grants Policy Statement (which generally means certain foreign activities can be included when well justified, even if the applicant organization itself must be domestic).
From an administrative standpoint, the opportunity is offered by the National Institutes of Health as a discretionary grant. The activity category is listed under education, environment, and health, and the CFDA/Assistance Listing numbers span multiple NIH institutes and centers (including 93.113, 93.121, 93.173, 93.213, 93.242, 93.273, 93.279, 93.307, 93.361, 93.853, 93.866, 93.867), reflecting that MOSAIC aligns with multiple NIH mission areas. The original closing date shown in the source data is 2024-07-24. The award ceiling and expected number of awards are not specified in the provided excerpt, which is common in NIH announcements where budgets depend on NIH policy caps for the mechanism and on institute-specific participation.
Overall, this funding opportunity is best understood as a targeted pathway for talented postdocs from diverse backgrounds who are ready to build independence but benefit from a structured bridge into faculty roles. It combines mentored-to-independent research support with a built-in cohort model and organized career development, with the explicit long-term aim of improving diversity and representation among independent investigators in the basic biomedical sciences and related NIH mission fields.Apply for PAR 21 273
- The National Institutes of Health in the education, environment, health sector is offering a public funding opportunity titled "Maximizing Opportunities for Scientific and Academic Independent Careers (MOSAIC) Postdoctoral Career Transition Award to Promote Diversity (K99/R00 - Independent Basic Experimental Studies with Humans Required (BESH))" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.113, 93.121, 93.173, 93.213, 93.242, 93.273, 93.279, 93.307, 93.361, 93.853, 93.866, 93.867.
- This funding opportunity was created on 2021-08-17.
- Applicants must submit their applications by 2024-07-24. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.
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| Funding Opportunity |
|---|
| Emerging Global Leader Award (K43 Independent Clinical Trial Not Allowed) Apply for PAR 21 252 Funding Number: PAR 21 252 Agency: National Institutes of Health Category: Education, Environment, Health Funding Amount: Case Dependent |
| Emerging Global Leader Award (K43 Independent Clinical Trial Required) Apply for PAR 21 251 Funding Number: PAR 21 251 Agency: National Institutes of Health Category: Education, Environment, Health Funding Amount: Case Dependent |
| Virtual Consortium for Translational/Transdisciplinary Environmental Research (ViCTER) (R01 Clinical Trial Optional) Apply for RFA ES 21 007 Funding Number: RFA ES 21 007 Agency: National Institutes of Health Category: Education, Environment, Health Funding Amount: $475,000 |
| Measures and Methods to Advance Research on Minority Health and Health Disparities-Related Constructs (R01 Clinical Trial Not Allowed) Apply for PAR 22 072 Funding Number: PAR 22 072 Agency: National Institutes of Health Category: Education, Environment, Health Funding Amount: $500,000 |
| Emergency Award: Rapid Acceleration of Diagnostics Tribal Data Repository (RADx TDR) (U24 Clinical Trial Not Allowed) Apply for RFA OD 22 011 Funding Number: RFA OD 22 011 Agency: National Institutes of Health Category: Education, Environment, Health Funding Amount: $2,000,000 |
| CCRP Initiative: Countermeasures Against Chemical Threats (CounterACT) Therapeutics Discovery and Early-Stage Development (UG3/UH3 Clinical Trial Not Allowed) Apply for PAR 22 209 Funding Number: PAR 22 209 Agency: National Institutes of Health Category: Education, Environment, Health Funding Amount: $350,000 |
| Multi-Omics for Health and Disease - Disease Study Sites (U01 Clinical Trial Optional) Apply for RFA HG 22 008 Funding Number: RFA HG 22 008 Agency: National Institutes of Health Category: Education, Environment, Health Funding Amount: $500,000 |
| Multi-Omics for Health and Disease - Data Analysis and Coordination Center (U01 Clinical Trial Not Allowed) Apply for RFA HG 22 010 Funding Number: RFA HG 22 010 Agency: National Institutes of Health Category: Education, Environment, Health Funding Amount: $950,000 |
| Multi-Omics for Health and Disease - 'Omics Production Centers (U01 Clinical Trial Not Allowed) Apply for RFA HG 22 009 Funding Number: RFA HG 22 009 Agency: National Institutes of Health Category: Education, Environment, Health Funding Amount: $2,700,000 |
| The Intersection of Sex and Gender Influences on Health and Disease (R01 Clinical Trial Optional) Apply for RFA OD 22 028 Funding Number: RFA OD 22 028 Agency: National Institutes of Health Category: Education, Environment, Health Funding Amount: $350,000 |
| Implementation Research on Noncommunicable Disease Risk Factors among Low- and Middle-Income Country and Tribal Populations Living in City Environments (R01 Clinical Trial Optional) Apply for PAR 23 042 Funding Number: PAR 23 042 Agency: National Institutes of Health Category: Education, Environment, Health Funding Amount: Case Dependent |
| Genomic Community Resources (U24 Clinical Trial Not Allowed) Apply for PAR 23 085 Funding Number: PAR 23 085 Agency: National Institutes of Health Category: Education, Environment, Health Funding Amount: Case Dependent |
| Biomedical Data Repository (U24 - Clinical Trials Not Allowed) Apply for PAR 23 079 Funding Number: PAR 23 079 Agency: National Institutes of Health Category: Education, Environment, Health Funding Amount: Case Dependent |
| Biomedical Knowledgebase (U24 - Clinical Trials Not Allowed) Apply for PAR 23 078 Funding Number: PAR 23 078 Agency: National Institutes of Health Category: Education, Environment, Health Funding Amount: Case Dependent |
| Time-Sensitive Research Opportunities in Environmental Health Sciences (R21 Clinical Trial Not Allowed) Apply for RFA ES 23 004 Funding Number: RFA ES 23 004 Agency: National Institutes of Health Category: Education, Environment, Health Funding Amount: Case Dependent |
| NIH Medical Scientist Partnership Program (FM1 Clinical Trial Not Allowed) Apply for PAR 23 109 Funding Number: PAR 23 109 Agency: National Institutes of Health Category: Education, Environment, Health Funding Amount: Case Dependent |
| CCRP Initiative: NIH Countermeasures Against Chemical Threats (CounterACT) Translational Exploratory/Developmental Research Projects (R21 Clinical Trial Not Allowed) Apply for PAR 23 139 Funding Number: PAR 23 139 Agency: National Institutes of Health Category: Education, Environment, Health Funding Amount: $275,000 |
| Limited Competition: Superfund Hazardous Substance Research and Training Program (P42 Clinical Trial Optional) Apply for RFA ES 23 001 Funding Number: RFA ES 23 001 Agency: National Institutes of Health Category: Education, Environment, Health Funding Amount: $2,000,000 |
| STrengthening Research Opportunities for NIH Grants (STRONG): Structured Institutional Needs Assessment and Action Plan Development for Resource Limited Institutions (RLIs) (UC2 - Clinical Trial Not Allowed) Apply for PAR 23 144 Funding Number: PAR 23 144 Agency: National Institutes of Health Category: Education, Environment, Health Funding Amount: $250,000 |
| Tobacco Regulatory Science (R01 Clinical Trial Optional) Apply for RFA OD 23 017 Funding Number: RFA OD 23 017 Agency: National Institutes of Health Category: Education, Environment, Health Funding Amount: $500,000 |
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