George M. O'Brien Kidney Research Core Centers (P30) | RFA DK 17 005

Opportunity Information: Apply for RFA DK 17 005

The George M. O'Brien Kidney Research Core Centers (P30) opportunity (RFA-DK-17-005) is a National Institutes of Health (NIH) grant program within the U.S. Department of Health and Human Services, focused on strengthening the national research infrastructure for kidney disease. The award supports the establishment or continuation of O'Brien Kidney Research Centers that bring together shared, state-of-the-art technologies, services, and scientific resources so that many investigators can use them efficiently. Rather than funding a single research project, this P30 mechanism is designed to build a hub of core resources that accelerates both basic and clinical kidney research by making specialized capabilities broadly accessible across an institution or consortium.

A central purpose of the program is to lower barriers to high-quality kidney research by creating shared cores that multiple research groups can rely on for advanced methods, tools, and expertise. These centers are expected to support studies spanning human kidney physiology and kidney disorders, with relevance to both patient-oriented research and work in animal or other experimental models. By concentrating high-end technologies and specialized know-how in a coordinated center structure, the program aims to improve rigor, reproducibility, and speed of discovery while reducing duplication of expensive infrastructure across individual labs.

The FOA highlights four major emphases. First, the centers should help attract new scientific expertise into kidney research and stimulate the development of new tools for studying kidney function and disease mechanisms in humans and in model systems. Second, the program prioritizes multidisciplinary research, encouraging collaboration across fields that can include basic science, clinical investigation, engineering, computational approaches, and other complementary disciplines. Third, the centers are encouraged to explore new research areas with translational potential, meaning directions that could reasonably bridge mechanistic findings toward diagnostics, prevention strategies, or therapeutic development. Fourth, the centers must generate Developmental Research (DR) and Pilot and Feasibility (P&F) projects, which are smaller, early-stage studies intended to seed innovative ideas, support new investigators or new collaborations, and produce preliminary data that can lead to larger, independent kidney disease research grants.

In terms of logistics and funding profile, the opportunity was listed as a discretionary grant under the NIH, cataloged under CFDA 93.847, with an activity category aligned to health (and noted as Food and Nutrition, Health in the source listing). The award ceiling shown is $750,000, and the expected number of awards is 4. The opportunity record shows a creation date of April 7, 2017, and an original closing date of November 1, 2017, indicating the specific posted round referenced in the source data.

Eligibility is broad and includes many types of U.S.-based organizations that commonly participate in federal biomedical research funding. Eligible applicants listed include state, county, and city/township governments; special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; Native American tribal governments (federally recognized) and tribal organizations (including those other than federally recognized tribal governments); public housing authorities/Indian housing authorities; nonprofit organizations with or without 501(c)(3) IRS status (excluding institutions of higher education in those nonprofit categories as written); for-profit organizations other than small businesses; small businesses; and additional eligible entities as described in the FOA text.

For applicants looking for context on how these centers are structured nationally and what existing O'Brien Kidney Research Core Centers provide, the announcement points to NIDDK's program page, which lists current centers and related information: https://www.niddk.nih.gov/research-funding/process/apply/about-funding-mechanisms/p30/pages/p30.aspx/.

• The Department of Health and Human Services, National Institutes of Health in the food and nutrition, health sector is offering a public funding opportunity titled "George M. O'Brien Kidney Research Core Centers (P30)" and is now available to receive applicants.
• Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.847.
• This funding opportunity was created on Apr 07, 2017.
• Applicants must submit their applications by Nov 01, 2017. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
• Each selected applicant is eligible to receive up to $750,000.00 in funding.
• The number of recipients for this funding is limited to 4 candidate(s).
• Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For profit organizations other than small businesses, Small businesses, Others (see text field entitled Additional Information on Eligibility for clarification).

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