Opportunity Information: Apply for RFA DK 17 005
The George M. O'Brien Kidney Research Core Centers (P30) opportunity (RFA-DK-17-005) is a National Institutes of Health (NIH) grant program within the U.S. Department of Health and Human Services, focused on strengthening the national research infrastructure for kidney disease. The award supports the establishment or continuation of O'Brien Kidney Research Centers that bring together shared, state-of-the-art technologies, services, and scientific resources so that many investigators can use them efficiently. Rather than funding a single research project, this P30 mechanism is designed to build a hub of core resources that accelerates both basic and clinical kidney research by making specialized capabilities broadly accessible across an institution or consortium.
A central purpose of the program is to lower barriers to high-quality kidney research by creating shared cores that multiple research groups can rely on for advanced methods, tools, and expertise. These centers are expected to support studies spanning human kidney physiology and kidney disorders, with relevance to both patient-oriented research and work in animal or other experimental models. By concentrating high-end technologies and specialized know-how in a coordinated center structure, the program aims to improve rigor, reproducibility, and speed of discovery while reducing duplication of expensive infrastructure across individual labs.
The FOA highlights four major emphases. First, the centers should help attract new scientific expertise into kidney research and stimulate the development of new tools for studying kidney function and disease mechanisms in humans and in model systems. Second, the program prioritizes multidisciplinary research, encouraging collaboration across fields that can include basic science, clinical investigation, engineering, computational approaches, and other complementary disciplines. Third, the centers are encouraged to explore new research areas with translational potential, meaning directions that could reasonably bridge mechanistic findings toward diagnostics, prevention strategies, or therapeutic development. Fourth, the centers must generate Developmental Research (DR) and Pilot and Feasibility (P&F) projects, which are smaller, early-stage studies intended to seed innovative ideas, support new investigators or new collaborations, and produce preliminary data that can lead to larger, independent kidney disease research grants.
In terms of logistics and funding profile, the opportunity was listed as a discretionary grant under the NIH, cataloged under CFDA 93.847, with an activity category aligned to health (and noted as Food and Nutrition, Health in the source listing). The award ceiling shown is $750,000, and the expected number of awards is 4. The opportunity record shows a creation date of April 7, 2017, and an original closing date of November 1, 2017, indicating the specific posted round referenced in the source data.
Eligibility is broad and includes many types of U.S.-based organizations that commonly participate in federal biomedical research funding. Eligible applicants listed include state, county, and city/township governments; special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; Native American tribal governments (federally recognized) and tribal organizations (including those other than federally recognized tribal governments); public housing authorities/Indian housing authorities; nonprofit organizations with or without 501(c)(3) IRS status (excluding institutions of higher education in those nonprofit categories as written); for-profit organizations other than small businesses; small businesses; and additional eligible entities as described in the FOA text.
For applicants looking for context on how these centers are structured nationally and what existing O'Brien Kidney Research Core Centers provide, the announcement points to NIDDK's program page, which lists current centers and related information: https://www.niddk.nih.gov/research-funding/process/apply/about-funding-mechanisms/p30/pages/p30.aspx/.Apply for RFA DK 17 005
- The Department of Health and Human Services, National Institutes of Health in the food and nutrition, health sector is offering a public funding opportunity titled "George M. O'Brien Kidney Research Core Centers (P30)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.847.
- This funding opportunity was created on Apr 07, 2017.
- Applicants must submit their applications by Nov 01, 2017. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $750,000.00 in funding.
- The number of recipients for this funding is limited to 4 candidate(s).
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For profit organizations other than small businesses, Small businesses, Others (see text field entitled Additional Information on Eligibility for clarification).
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Frequently Asked Questions (FAQs): George M. O'Brien Kidney Research Core Centers (P30) - RFA-DK-17-005
What is the George M. O'Brien Kidney Research Core Centers (P30) opportunity?
This opportunity is an NIH grant program (within the U.S. Department of Health and Human Services) that supports the establishment or continuation of George M. O'Brien Kidney Research Centers. It is focused on strengthening the national research infrastructure for kidney disease by building shared, state-of-the-art core resources that many investigators can use efficiently.
What is the funding mechanism for this opportunity?
The mechanism is a P30 Center Core Grant. Rather than funding a single research project, a P30 supports a hub of shared scientific resources, technologies, services, and expertise designed to enable and accelerate multiple kidney research projects across an institution or consortium.
What is the FOA number and program name associated with this grant?
The opportunity is titled "The George M. O'Brien Kidney Research Core Centers (P30)" and is associated with FOA number RFA-DK-17-005.
Which federal agency administers this grant?
The opportunity is administered by the National Institutes of Health (NIH), within the U.S. Department of Health and Human Services.
What is the overall purpose of the O'Brien Kidney Research Centers supported by this program?
The central purpose is to lower barriers to high-quality kidney research by creating shared cores that multiple research groups can rely on for advanced methods, tools, and expertise. The centers are intended to improve rigor, reproducibility, and speed of discovery while reducing duplication of expensive infrastructure across individual labs.
Does this grant fund a single research project?
No. This is not designed to fund one stand-alone research project. It supports a center structure with shared core resources that enable many investigators to conduct basic and clinical kidney research more efficiently.
What types of research are these centers expected to support?
The centers are expected to support studies spanning human kidney physiology and kidney disorders. The scope includes relevance to patient-oriented research as well as work in animal or other experimental model systems.
What kinds of resources or services are expected to be provided by an O'Brien Kidney Research Center?
The award supports shared, state-of-the-art technologies, services, and scientific resources. The program emphasizes specialized capabilities and coordinated center structures so that investigators can access high-end technologies and expert know-how broadly across an institution or consortium.
What are the major emphasis areas highlighted in the FOA?
The FOA describes four major emphases: (1) attracting new scientific expertise into kidney research and stimulating development of new tools for studying kidney function and disease mechanisms in humans and model systems; (2) prioritizing multidisciplinary research and collaboration across fields; (3) exploring new research areas with translational potential (bridging mechanistic findings toward diagnostics, prevention strategies, or therapeutics); and (4) generating Developmental Research (DR) and Pilot and Feasibility (P&F) projects to seed innovation and produce preliminary data for future independent grants.
What does "multidisciplinary" mean in the context of this program?
The program encourages collaboration across complementary disciplines. Examples named in the FOA include basic science, clinical investigation, engineering, and computational approaches, among other relevant fields.
What does "translational potential" mean for the research areas encouraged by the centers?
In this context, translational potential refers to directions that could reasonably bridge mechanistic findings toward practical outcomes such as diagnostics, prevention strategies, or therapeutic development.
What are Developmental Research (DR) projects?
Developmental Research (DR) projects are smaller, early-stage studies generated by the centers to seed innovative ideas, support investigators (including new investigators), encourage new collaborations, and generate preliminary data that can lead to larger, independent kidney disease research grants.
What are Pilot and Feasibility (P&F) projects?
Pilot and Feasibility (P&F) projects are small, early-stage studies supported through the center. They are intended to seed new ideas, support new investigators or new collaborations, and produce preliminary results that can underpin subsequent, larger kidney disease research grant applications.
How does this program help reduce barriers to kidney research?
By concentrating advanced technologies, specialized tools, and expert services into shared cores, the centers make high-end capabilities broadly accessible, reduce duplication of expensive infrastructure across laboratories, and support more consistent methods that improve rigor and reproducibility.
What is the maximum award amount listed for this opportunity?
The award ceiling shown in the opportunity listing is $750,000.
How many awards were expected under the referenced posting?
The expected number of awards listed is 4.
What is the CFDA number associated with this opportunity?
The opportunity is cataloged under CFDA 93.847.
How is the opportunity categorized in the source listing?
The opportunity is listed as a discretionary grant under NIH, with an activity category aligned to health (and noted as "Food and Nutrition, Health" in the source listing).
What were the key dates shown in the opportunity record?
The record shows a creation date of April 7, 2017, and an original closing date of November 1, 2017. These dates reflect the specific posted round referenced in the source data.
Who is eligible to apply for this P30 opportunity?
Eligibility is broad and includes many U.S.-based organizations commonly involved in federal biomedical research funding. The listed eligible applicants include state, county, and city/township governments; special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; Native American tribal governments (federally recognized) and tribal organizations (including those other than federally recognized tribal governments); public housing authorities/Indian housing authorities; nonprofit organizations with or without 501(c)(3) IRS status (excluding institutions of higher education in those nonprofit categories as written); for-profit organizations other than small businesses; small businesses; and additional eligible entities as described in the FOA text.
Are institutions of higher education eligible?
Yes. The eligibility list explicitly includes both public and state-controlled institutions of higher education and private institutions of higher education.
Are tribal governments or tribal organizations eligible?
Yes. The eligibility list includes Native American tribal governments (federally recognized) and tribal organizations (including those other than federally recognized tribal governments).
Are for-profit entities eligible to apply?
Yes. The eligibility list includes for-profit organizations other than small businesses, and it also includes small businesses.
Are nonprofit organizations eligible to apply?
Yes. The eligibility list includes nonprofit organizations with or without 501(c)(3) IRS status (excluding institutions of higher education in those nonprofit categories as written in the listing).
Does the opportunity support establishing a new center as well as continuing an existing center?
Yes. The award supports the establishment or continuation of O'Brien Kidney Research Centers.
Where can applicants find context on existing O'Brien Kidney Research Core Centers?
The announcement points to NIDDK's program page, which lists current centers and related information: https://www.niddk.nih.gov/research-funding/process/apply/about-funding-mechanisms/p30/pages/p30.aspx/.
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